Glutathione-CoA-glutathione transhydrogenase

Glutathione-CoA-glutathione transhydrogenase

In enzymology, a glutathione---CoA-glutathione transhydrogenase (EC number|1.8.4.3) is an enzyme that catalyzes the chemical reaction

:CoA + glutathione disulfide ightleftharpoons CoA-glutathione + glutathione

Thus, the two substrates of this enzyme are CoA and glutathione disulfide, whereas its two products are CoA-glutathione and glutathione.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is CoA:glutathione-disulfide oxidoreductase. Other names in common use include glutathione-coenzyme A glutathione disulfide transhydrogenase, glutathione-coenzyme A glutathione disulfide transhydrogenase, glutathione coenzyme A-glutathione transhydrogenase, glutathione:coenzyme A-glutathione transhydrogenase, coenzyme A:oxidized-glutathione oxidoreductase, and coenzyme A:glutathione-disulfide oxidoreductase. This enzyme participates in cysteine metabolism and glutathione metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37256-48-7."

Gene Ontology (GO) codes


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