- D-nopaline dehydrogenase
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D-nopaline dehydrogenase Identifiers EC number 1.5.1.19 CAS number 64763-57-1 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a D-nopaline dehydrogenase (EC 1.5.1.19) is an enzyme that catalyzes the chemical reaction
- N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O
L-arginine + 2-oxoglutarate + NADPH + H+
The 3 substrates of this enzyme are N2-(D-1,3-dicarboxypropyl)-L-arginine, NADP+, and H2O, whereas its 4 products are L-arginine, 2-oxoglutarate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming). Other names in common use include D-nopaline synthase, nopaline dehydrogenase, nopaline synthase, NOS, 2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase, and (L-arginine-forming). This enzyme participates in arginine and proline metabolism.
References
- Kemp JD, Sutton DW, Hack E (1979). "Purification and characterization of the crown gall specific enzyme nopaline synthase". Biochemistry. 18 (17): 3755–60. doi:10.1021/bi00584a017. PMID 476084.
This EC 1.5 enzyme-related article is a stub. You can help Wikipedia by expanding it. - N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O
