Azobenzene reductase

Azobenzene reductase

In enzymology, an azobenzene reductase (EC number| is an enzyme that catalyzes the chemical reaction

:N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ ightleftharpoons 4-(dimethylamino)azobenzene + NADPH + H+

The 3 substrates of this enzyme are N,N-dimethyl-1,4-phenylenediamine, aniline, and NADP+, whereas its 3 products are 4-(dimethylamino)azobenzene, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase. Other names in common use include new coccine (NC)-reductase, NC-reductase, azo-dye reductase, orange II azoreductase, NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase, orange I azoreductase, azo reductase, azoreductase, nicotinamide adenine dinucleotide (phosphate) azoreductase, NADPH2-dependent azoreductase, dimethylaminobenzene reductase, p-dimethylaminoazobenzene azoreductase, dibromopropylaminophenylazobenzoic azoreductase, N,N-dimethyl-4-phenylazoaniline azoreductase, p-aminoazobenzene reductase, methyl red azoreductase, and NADPH2:4-(dimethylamino)azobenzene oxidoreductase.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1NNI, PDB link|1V4B, and PDB link|2D5I.



External links

::"The CAS registry number for this enzyme class is CAS registry|9029-31-6."

Gene Ontology (GO) codes

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  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

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