Azobenzene reductase

In enzymology, an azobenzene reductase (EC number|1.7.1.6) is an enzyme that catalyzes the chemical reaction

:N,N-dimethyl-1,4-phenylenediamine + aniline + NADP⁺ $ightleftharpoons$ 4-(dimethylamino)azobenzene + NADPH + H⁺

The 3 substrates of this enzyme are N,N-dimethyl-1,4-phenylenediamine, aniline, and NADP⁺, whereas its 3 products are 4-(dimethylamino)azobenzene, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase. Other names in common use include new coccine (NC)-reductase, NC-reductase, azo-dye reductase, orange II azoreductase, NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase, orange I azoreductase, azo reductase, azoreductase, nicotinamide adenine dinucleotide (phosphate) azoreductase, NADPH2-dependent azoreductase, dimethylaminobenzene reductase, p-dimethylaminoazobenzene azoreductase, dibromopropylaminophenylazobenzoic azoreductase, N,N-dimethyl-4-phenylazoaniline azoreductase, p-aminoazobenzene reductase, methyl red azoreductase, and NADPH2:4-(dimethylamino)azobenzene oxidoreductase.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1NNI, PDB link|1V4B, and PDB link|2D5I.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-31-6."

Gene Ontology (GO) codes