Tryptophan 2'-dioxygenase
- Tryptophan 2'-dioxygenase
In enzymology, a tryptophan 2'-dioxygenase (EC number|1.13.99.3) is an enzyme that catalyzes the chemical reaction
:L-tryptophan + O2 (indol-3-yl)glycolaldehyde + CO2 + NH3
Thus, the two substrates of this enzyme are L-tryptophan and O2, whereas its 3 products are (indol-3-yl)glycolaldehyde, CO2, and NH3.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O miscellaneous. The systematic name of this enzyme class is L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving). Other names in common use include indole-3-alkane alpha-hydroxylase, tryptophan side-chain alpha,beta-oxidase, tryptophan side chain oxidase II, tryptophan side-chain oxidase, TSO, indolyl-3-alkan alpha-hydroxylase, tryptophan side chain oxidase type I, TSO I, TSO II, and tryptophan side chain oxidase. This enzyme participates in tryptophan metabolism. It employs one cofactor, heme.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|64295-81-4."
Gene Ontology (GO) codes
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