Hydrogen dehydrogenase (NADP+)

Hydrogen dehydrogenase (NADP+)

In enzymology, a hydrogen dehydrogenase (NADP+) (EC number|1.12.1.3) is an enzyme that catalyzes the chemical reaction

:H2 + NADP+ ightleftharpoons H+ + NADPH

Thus, the two substrates of this enzyme are H2 and NADP+, whereas its two products are H+ and NADPH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydrogen:NADP+ oxidoreductase. Other names in common use include NADP+-linked hydrogenase, NADP+-reducing hydrogenase, hydrogen dehydrogenase (NADP+), and simply hydrogenase (which is ambiguous).

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2AUV.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9027-05-8."

Gene Ontology (GO) codes


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