Coenzyme F420 hydrogenase

coenzyme F420 hydrogenase
Identifiers
EC number	1.12.98.1
CAS number	9027-05-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a coenzyme F420 hydrogenase (EC 1.12.98.1) is an enzyme that catalyzes the chemical reaction

H₂ + coenzyme F₄₂₀ $\rightleftharpoons$ reduced coenzyme F₄₂₀

Thus, the two substrates of this enzyme are H₂ and coenzyme F420, whereas its product is reduced coenzyme F420.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other, known, acceptors. The systematic name of this enzyme class is hydrogen:coenzyme F420 oxidoreductase. Other names in common use include 8-hydroxy-5-deazaflavin-reducing hydrogenase, F420-reducing hydrogenase, and coenzyme F420-dependent hydrogenase. This enzyme participates in folate biosynthesis. It has 3 cofactors: iron, nickel, and deazaflavin.

References

• Adams MWW, Mortenson LE and Chen J-S (1981). "Hydrogenase". Biochim. Biophys. Acta 594: 105–176. 
• Yamazaki S (1982). "A selenium-containing hydrogenase from Methanococcus vannielii Identification of the selenium moiety as a selenocysteine residue". J. Biol. Chem. 257 (14): 7926–9. PMID 6211447. 
• Fox JA, Livingston DJ, Orme-Johnson WH, Walsh CT (1987). "8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization". Biochemistry. 26 (14): 4219–27. doi:10.1021/bi00388a007. PMID 3663585. 
• Muth E, Morschel E, Klein A (1987). "Purification and characterization of an 8-hydroxy-5-deazaflavin-reducing hydrogenase from the archaebacterium Methanococcus voltae". Eur. J. Biochem. 169 (3): 571–7. doi:10.1111/j.1432-1033.1987.tb13647.x. PMID 3121317. 
• Baron SF, Ferry JG (1989). "Purification and properties of the membrane-associated coenzyme F420-reducing hydrogenase from Methanobacterium formicicum". J. Bacteriol. 171 (7): 3846–53. PMC 210134. PMID 2738024. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=210134. 

This EC 1.12 enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Oxidoreductase stubs EC 1.12.98 Iron enzymes Nickel enzymes Deazaflavin enzymes Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Igor Savchenko Perils of the Royal Mounted Look at other dictionaries: Coenzyme F420 — Structure of Coenzyme F420 Coenzyme F420 or 8 hydroxy 5 deazaflavin is a coenzyme involved in redox reactions in methanogens [1], in many Actinobacteria, and sporadically in other bacterial lineages. It is a flavin derivative. The coenzyme is a… …   Wikipedia Coenzyme F420 — Structure de la coenzyme F420. Général No CAS …   Wikipédia en Français Hydrogenase — A hydrogenase is an enzyme that catalyses the reversible oxidation of molecular hydrogen (H2). Hydrogenases play a vital role in anaerobic metabolism. [cite journal | author=Adams, M.W.W. and Stiefel, E.I. | title=Biological hydrogen production:… …   Wikipedia F420 — Strukturformel Allgemeines Name F420 Andere Namen Coenzym F420 …   Deutsch Wikipedia Кофермент F420 — (Coenzyme F420) или 8 гидрокси 5 деазофлавин  это кофермент, участвующий в восстановительных реакциях у продуцентов метана,[1] например, у Methanosarcina barkeri. Это производное флавина. Данный кофермент является субстратом для гидрогеназы… …   Википедия List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia Tetrahydromethanopterin — Identifiers PubChem 5459995 …   Wikipedia Méthanogenèse — La méthanogenèse, ou biométhanation, désigne l ensemble des voies métaboliques produisant du méthane CH4 chez certains microorganismes qualifiés de méthanogènes. De tels microorganismes n ont été identifiés qu au sein du domaine des archées, un… …   Wikipédia en Français Cofactor (biochemistry) — The succinate dehydrogenase complex showing several cofactors, including flavin, iron sulfur centers, and heme. A cofactor is a non protein chemical compound that is bound to a protein and is required for the protein s biolog …   Wikipedia Metalloprotein — The structure of hemoglobin. The heme cofactor, containing iron, shown in green. Metalloprotein is a generic term for a protein that contains a metal ion cofactor.[1] Metalloproteins have many different functions in cells …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”