Ferredoxin-NADP+ reductase

In enzymology, a ferredoxin---NADP+ reductase (EC number|1.18.1.2) is an enzyme that catalyzes the chemical reaction

:2 reduced ferredoxin + NADP⁺ + H⁺ $ightleftharpoons$ 2 oxidized ferredoxin + NADPH

The 3 substrates of this enzyme are reduced ferredoxin, NADP⁺, and H⁺, whereas its two products are oxidized ferredoxin and NADPH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on iron-sulfur proteins as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ferredoxin:NADP+ oxidoreductase. Other names in common use include adrenodoxin reductase, ferredoxin-nicotinamide adenine dinucleotide phosphate reductase, ferredoxin-NADP+ reductase, TPNH-ferredoxin reductase, ferredoxin-NADP+ oxidoreductase, NADP+:ferredoxin oxidoreductase, ferredoxin-TPN reductase, reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin, reductase, ferredoxin-NADP+-oxidoreductase, NADPH:ferredoxin oxidoreductase, ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized), reductase, and ferredoxin---NADP+ reductase. This enzyme participates in photosynthesis. It has 2 cofactors: FAD, and Flavin.

tructural studies

As of late 2007, 54 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1B2R, PDB link|1BJK, PDB link|1BQE, PDB link|1BX0, PDB link|1BX1, PDB link|1CJC, PDB link|1E1L, PDB link|1E62, PDB link|1E63, PDB link|1E64, PDB link|1E6E, PDB link|1EWY, PDB link|1FDR, PDB link|1FNB, PDB link|1FNC, PDB link|1FND, PDB link|1FRN, PDB link|1FRQ, PDB link|1GAQ, PDB link|1GAW, PDB link|1GJR, PDB link|1GO2, PDB link|1GR1, PDB link|1H42, PDB link|1H85, PDB link|1JB9, PDB link|1OGI, PDB link|1OGJ, PDB link|1QFY, PDB link|1QFZ, PDB link|1QG0, PDB link|1QGA, PDB link|1QGY, PDB link|1QGZ, PDB link|1QH0, PDB link|1QUE, PDB link|1QUF, PDB link|1SM4, PDB link|1W34, PDB link|1W35, PDB link|1W87, PDB link|2B5O, PDB link|2BGI, PDB link|2BGJ, PDB link|2BMW, PDB link|2BSA, PDB link|2C7G, PDB link|2GQW, PDB link|2GR0, PDB link|2GR1, PDB link|2GR2, PDB link|2GR3, PDB link|2OK7, and PDB link|2OK8.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-33-8."

Gene Ontology (GO) codes