- 4-hydroxybenzaldehyde dehydrogenase
-
4-hydroxybenzaldehyde dehydrogenase Identifiers EC number 1.2.1.64 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a 4-hydroxybenzaldehyde dehydrogenase (EC 1.2.1.64) is an enzyme that catalyzes the chemical reaction
- 4-hydroxybenzaldehyde + NAD+ + H2O
4-hydroxybenzoate + NADH + 2 H+
The 3 substrates of this enzyme are 4-hydroxybenzaldehyde, NAD+, and H2O, whereas its 3 products are 4-hydroxybenzoate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-hydroxybenzaldehyde:NAD+ oxidoreductase. This enzyme is also called p-hydroxybenzaldehyde dehydrogenase. This enzyme participates in toluene and xylene degradation.
References
- Bossert ID, Whited G, Gibson DT, Young LY (1989). "Anaerobic oxidation of p-cresol mediated by a partially purified methylhydroxylase from a denitrifying bacterium". J. Bacteriol. 171 (6): 2956–62. PMC 210000. PMID 2722739. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=210000.
- Whited GM, Gibson DT (1991). "Separation and partial characterization of the enzymes of the toluene-4-monooxygenase catabolic pathway in Pseudomonas mendocina KR1". J. Bacteriol. 173 (9): 3017–20. PMC 207886. PMID 2019564. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=207886.
This EC 1.2 enzyme-related article is a stub. You can help Wikipedia by expanding it. - 4-hydroxybenzaldehyde + NAD+ + H2O
