Mannitol dehydrogenase (cytochrome)

Mannitol dehydrogenase (cytochrome)
mannitol dehydrogenase (cytochrome)
EC number
CAS number 37250-78-5
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a mannitol dehydrogenase (cytochrome) (EC is an enzyme that catalyzes the chemical reaction

D-mannitol + ferricytochrome c \rightleftharpoons D-fructose + ferrocytochrome c

Thus, the two substrates of this enzyme are D-mannitol and ferricytochrome c, whereas its two products are D-fructose and ferrocytochrome c.

This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-OH group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is D-mannitol:ferricytochrome-c 2-oxidoreductase. This enzyme is also called polyol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.


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