Benzoyl-CoA reductase

In enzymology, a benzoyl-CoA reductase (EC number|1.3.99.15) is an enzyme that catalyzes the chemical reaction

:benzoyl-CoA + reduced acceptor + 2 ATP + 2 H₂O $ightleftharpoons$ cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate

The 4 substrates of this enzyme are benzoyl-CoA, reduced acceptor, ATP, and H₂O, whereas its 4 products are cyclohexa-1,5-diene-1-carbonyl-CoA, acceptor, ADP, and phosphate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is cyclohexa-1,5-diene-1-carbonyl-CoA:acceptor oxidoreductase (aromatizing, ATP-forming). This enzyme is also called benzoyl-CoA reductase (dearomatizing). This enzyme participates in benzoate degradation via coa ligation. It has 2 cofactors: manganese, and Magnesium.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|176591-18-7."

Gene Ontology (GO) codes