4-hydroxybenzoyl-CoA reductase
- 4-hydroxybenzoyl-CoA reductase
In enzymology, a 4-hydroxybenzoyl-CoA reductase (EC number|1.3.99.20) is an enzyme that catalyzes the chemical reaction
:benzoyl-CoA + acceptor + H2O 4-hydroxybenzoyl-CoA + reduced acceptor
The 3 substrates of this enzyme are benzoyl-CoA, acceptor, and H2O, whereas its two products are 4-hydroxybenzoyl-CoA and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is benzoyl-CoA:acceptor oxidoreductase. Other names in common use include 4-hydroxybenzoyl-CoA reductase (dehydroxylating), and 4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.
tructural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1RM6 and PDB link|1SB3.
References
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External links
Gene Ontology (GO) codes
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