- Methylene-fatty-acyl-phospholipid synthase
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methylene-fatty-acyl-phospholipid synthase Identifiers EC number 2.1.1.16 CAS number 37256-90-9 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a methylene-fatty-acyl-phospholipid synthase (EC 2.1.1.16) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + phospholipid olefinic fatty acid S-adenosyl-L-homocysteine + phospholipid methylene fatty acid
Thus, the two substrates of this enzyme are S-adenosyl methionine and phospholipid olefinic fatty acid, whereas its two products are S-adenosylhomocysteine and phospholipid methylene fatty acid.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating). This enzyme is also called unsaturated-phospholipid methyltransferase.
References
- Akamatsu Y, Law JH (1970). "Enzymatic alkylenation of phospholipid fatty acid chains by extracts of Mycobacterium phlei". J. Biol. Chem. 245 (4): 701–8. PMID 4313604.
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