Methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase

Methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase

In enzymology, a methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (EC number|2.1.1.74) is an enzyme that catalyzes the chemical reaction

:5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2 ightleftharpoons tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD

The 3 substrates of this enzyme are 5,10-methylenetetrahydrofolate, tRNA containing uridine at position 54, and FADH2, whereas its 3 products are tetrahydrofolate, tRNA containing ribothymidine at position 54, and FAD.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyl-transferase. Other names in common use include (FADH2-oxidizing), folate-dependent ribothymidyl synthase, methylenetetrahydrofolate-transfer ribonucleate uracil, 5-methyltransferase, 5,10-methylenetetrahydrofolate:tRNA-UPsiC, and (uracil-5-)-methyl-transferase.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|74665-78-4."

Gene Ontology (GO) codes


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Look at other dictionaries:

  • Methylenetetrahydrofolate—tRNA-(uracil-5-)-methyltransferase — (FADH2 oxidizing) Identifiers EC number 2.1.1.74 CAS number 74665 78 4 …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

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