- Cycloartenol 24-C-methyltransferase
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cycloartenol 24-C-methyltransferase Identifiers EC number 2.1.1.142 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cycloartenol 24-C-methyltransferase (EC 2.1.1.142) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + cycloartenol S-adenosyl-L-homocysteine + (24R)-24-methylcycloart-25-en-3beta-ol
Thus, the two substrates of this enzyme are S-adenosyl methionine and cycloartenol, whereas its two products are S-adenosylhomocysteine and (24R)-24-methylcycloart-25-en-3beta-ol.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase. This enzyme is also called sterol C-methyltransferase.
References
- Mangla AT, Nes WD (2000). "Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition". Bioorg. Med. Chem. 8 (5): 925–36. doi:10.1016/S0968-0896(00)00040-7. PMID 10882005.
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