- Columbamine O-methyltransferase
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columbamine O-methyltransferase Identifiers EC number 2.1.1.118 CAS number 105843-76-3 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a columbamine O-methyltransferase (EC 2.1.1.118) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + columbamine
S-adenosyl-L-homocysteine + palmatine
Thus, the two substrates of this enzyme are S-adenosyl methionine and columbamine, whereas its two products are S-adenosylhomocysteine and palmatine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:columbamine O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
- Rueffer M, Amann M, Zenk MH (1986). "S-Adenosyl-L-methionine:columbamine O-methyltransferase, a compartmentalized enzyme in protoberberine biosynthesis". Plant Cell Reports 3: 182–185.
This transferase article is a stub. You can help Wikipedia by expanding it. - S-adenosyl-L-methionine + columbamine
