Fibrin degradation product
- Fibrin degradation product
Fibrin degradation product (FDPs) are components of the blood produced by clot degeneration.[cite journal |author=Gaffney PJ, Edgell T, Creighton-Kempsford LJ, Wheeler S, Tarelli E |title=Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma |journal=Br. J. Haematol. |volume=90 |issue=1 |pages=187–94 |year=1995 |pmid=7786784 |doi=] These are produced by the action of Plasmin on deposited fibrin.]The levels of these FDPs rises after any thrombotic event.
It can be used to test for disseminated intravascular coagulation. [ [http://peir.path.uab.edu/coag/article_77.shtml Fibrin/Fibrinogen Degradation Products ] ]
ee also
* fibrin
References
External links
*
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2010.
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D-dimer — is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrinogen protein.[1] D dimer… … Wikipedia
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D dimer — a fibrin degradation product containing a cross link between two fibrin monomers; the cross link does not occur in fibrinogen, so that tests for D dimer are specific for fibrin. See D dimer assay, under assay … Medical dictionary
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D-dimer assay — an immunoassay for the fibrin degradation product D dimer. Levels are elevated in deep venous thrombosis, acute myocardial infarction, pulmonary embolism, unstable angina, and disseminated intravascular coagulation (DIC). Called also D dimer test … Medical dictionary
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Fibrinolysis — is a process that prevents blood clots from growing and becoming problematic.[1] This process has two types: primary fibrinolysis and secondary fibrinolysis. The primary type is a normal body process, whereas secondary fibrinolysis is the… … Wikipedia
