5-amino-6-(5-phosphoribosylamino)uracil reductase

5-amino-6-(5-phosphoribosylamino)uracil reductase

In enzymology, a 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC number|1.1.1.193) is an enzyme that catalyzes the chemical reaction

:5-amino-6-(5-phosphoribitylamino)uracil + NADP+ ightleftharpoons 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+

Thus, the two substrates of this enzyme are 5-amino-6-(5-phosphoribitylamino)uracil and NADP+, whereas its 3 products are 5-amino-6-(5-phosphoribosylamino)uracil, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase. This enzyme is also called aminodioxyphosphoribosylaminopyrimidine reductase. This enzyme participates in riboflavin metabolism.

tructural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2AZN, PDB link|2B3Z, PDB link|2D5N, PDB link|2G6V, PDB link|2HXV, PDB link|2O7P, and PDB link|2OBC.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|69020-28-6."

Gene Ontology (GO) codes


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Look at other dictionaries:

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • Diaminohydroxyphosphoribosylaminopyrimidine deaminase — Identifiers EC number 3.5.4.26 CAS number 68994 19 4 …   Wikipedia

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