3-keto-steroid reductase

3-keto-steroid reductase

In enzymology, a 3-keto-steroid reductase (EC number|1.1.1.270) is an enzyme that catalyzes the chemical reaction

:4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP+ ightleftharpoons 4alpha-methyl-5alpha-cholest-7-en-3-one + NADPH + H+

Thus, the two substrates of this enzyme are 4alpha-methyl-5alpha-cholest-7-en-3beta-ol and NADP+, whereas its 3 products are 4alpha-methyl-5alpha-cholest-7-en-3-one, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3beta-hydroxy-steroid:NADP+ 3-oxidoreductase. This enzyme is also called 3-KSR. This enzyme participates in biosynthesis of steroids.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|42616-29-5."

Gene Ontology (GO) codes


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