N-acetylhexosamine 1-dehydrogenase

N-acetylhexosamine 1-dehydrogenase
N-acetylhexosamine 1-dehydrogenase
Identifiers
EC number 1.1.1.240
CAS number 122785-18-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-acetylhexosamine 1-dehydrogenase (EC 1.1.1.240) is an enzyme that catalyzes the chemical reaction

N-acetyl-D-glucosamine + NAD+ \rightleftharpoons N-acetyl-D-glucosaminate + NADH + H+

Thus, the two substrates of this enzyme are N-acetyl-D-glucosamine and NAD+, whereas its 3 products are N-acetyl-D-glucosaminate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase. Other names in common use include N-acetylhexosamine dehydrogenase, and N-acetyl-D-hexosamine dehydrogenase.

References

  • Horiuchi T and Kurokawa T (1989). "Purification and characterization of N-acetyl-D-hexosamine dehydrogenase from Pseudomonas sp no 53". Agric. Biol. Chem. 53 (7): 1919–1925. doi:10.1271/bbb1961.53.1919. 
This EC 1.1.1 enzyme-related article is a stub. You can help Wikipedia by expanding it.