- Cyclopentanol dehydrogenase
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cyclopentanol dehydrogenase Identifiers EC number 1.1.1.163 CAS number 37364-12-8 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cyclopentanol dehydrogenase (EC 1.1.1.163) is an enzyme that catalyzes the chemical reaction
- cyclopentanol + NAD+
cyclopentanone + NADH + H+
Thus, the two substrates of this enzyme are cyclopentanol and NAD+, whereas its 3 products are cyclopentanone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cyclopentanol:NAD+ oxidoreductase.
References
- Griffin M, Trudgill PW (1972). "The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872". Biochem. J. 129 (3): 595–603. PMC 1174162. PMID 4349113. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1174162.
- Iwaki H, Hasegawa Y, Wang S, Kayser MM, Lau PC (2002). "Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase". Appl. Environ. Microbiol. 68 (11): 5671–84. doi:10.1128/AEM.68.11.5671-5684.2002. PMC 129933. PMID 12406764. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=129933.
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