Trans-endocytosis

Trans-endocytosis

Trans-endocytosis is the biological process where material created in one cell undergoes endocytosis (enters) into another cell. If the material is large enough, this can be observed using an electron microscope. [cite journal
author=Spacek J
coauthors=Harris K.
year=2004
month=Apr
title=Trans-endocytosis via spinules in adult rat hippocampus
journal=J Neurosci.
volume=24
issue=17
pages=4233–4241
pmid=15115819
doi=10.1523/JNEUROSCI.0287-04.2004] Trans-endocytosis from neurons to glia has been observed using time-lapse microscopy. [cite journal
author=Lauterbach J
coauthors=Klein R.
year=2006
month=Nov
title=Release of full-length EphB2 receptors from hippocampal neurons to cocultured glial cells
journal=J Neurosci.
volume=26
issue=45
pages=11575–11581
pmid=17093078
doi=10.1523/JNEUROSCI.2697-06.2006]

Trans-endocytosis also applies to molecules. For example, this process is involved when a part of the protein Notch is cleaved off and undergoes endocytosis into its neighboring cell. [cite journal
author=Krämer H.
title=RIPping notch apart: a new role for endocytosis in signal transduction?
journal=Sci STKE.
year=2000
month=Apr
volume=2000
issue=29
pages=pe1
pmid=11752592] [cite journal
author=Parks AL
coauthors=Klueg KM, Stout JR, Muskavitch MA.
year=2000
month=Apr
title=Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
journal=Development
volume=127
issue=7
pages=1373–1385
pmid=10704384] Without Notch trans-endocytosis, there would be too many neurons in a developing embryo. [cite journal
author=Klueg KM
coauthors=Muskavitch MA.
year=1999
month=Oct
title=Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila
journal=J Cell Sci.
volume=112
issue=19
pages=3289–3297
pmid=10504334] Trans-endocytosis is also involved in cell movement when the protein ephrin is bound by its receptor from a neighboring cell. [cite journal
author=Marston DJ
coauthors=Dickinson S, Nobes CD.
year=2003
month=Oct
title=Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion
journal=Nat Cell Biol.
volume=5
issue=
pages=879–888
pmid=12973357
doi=10.1038/ncb1044]

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Cholesterol — IUPAC name …   Wikipedia

  • Active transport — This article is about transport in cellular biology. For human transport systems, see active transportation. The action of the sodium potassium pump is an example of primary active transport. Active transport is the movement of a substance… …   Wikipedia

  • Endomembrane system — The endomembrane system is composed of the different membranes that are suspended in the cytoplasm within a eukaryotic cell. These membranes divide the cell into functional and structural compartments, or organelles. The organelles of the… …   Wikipedia

  • Gene therapy — using an Adenovirus vector. A new gene is inserted into an adenovirull. If the treatment is successful, the new gene will make a functional protein. Gene therapy is the insertion, alteration, or removal of genes within an individual s cells and… …   Wikipedia

  • Clathrin — clathrin, light polypeptide (Lca) Identifiers Symbol CLTA Entrez 1211 HUGO …   Wikipedia

  • Stratégies pour franchir la barrière hémato-encéphalique — Traduction à relire …   Wikipédia en Français

  • Transport à la barrière hémato-encéphalique — Traduction à relire Blut Hirn Schranke …   Wikipédia en Français

  • cell — cell1 cell like, adj. /sel/, n. 1. a small room, as in a convent or prison. 2. any of various small compartments or bounded areas forming part of a whole. 3. a small group acting as a unit within a larger organization: a local cell of the… …   Universalium

  • AP1M1 — Adaptor related protein complex 1, mu 1 subunit, also known as AP1M1, is a human gene. PBB Summary section title = summary text = The protein encoded by this gene is the medium chain of the trans Golgi network clathrin associated protein complex… …   Wikipedia

  • Blut-Gehirn-Schranke — Die Blut Hirn Schranke, auch Blut Gehirn Schranke genannt, ist eine bei allen Landwirbeltieren (Tetrapoda) im Gehirn vorhandene physiologische Barriere zwischen dem Blutkreislauf und dem Zentralnervensystem. Sie dient dazu, die Milieubedingungen… …   Deutsch Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”