PA 824

PA 824: PA 824

IUPAC name

(6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine

Identifiers

CAS number 187235-37-6^Y

PubChem 456199

MeSH PA+824

ChEMBL CHEMBL227875^N

Jmol-3D images Image 1

SMILES

[O-][N+](=O)c1cn2C[C@@H](COc2n1)OCc3ccc(OC(F)(F)F)cc3

Properties

Molecular formula C₁₄H₁₂F₃N₃O₅

Molar mass 359.258 g/mol

N 824 (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

PA 824 is an experimental anti-tuberculosis drug.^[1]^[2]

References

^ Ginsberg AM, Laurenzi MW, Rouse DJ, Whitney KD, Spigelman MK (September 2009). "Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects". Antimicrob. Agents Chemother. 53 (9): 3720–5. doi:10.1128/AAC.00106-09. PMC 2737845. PMID 19528280. http://aac.asm.org/cgi/pmidlookup?view=long&pmid=19528280.

^ Stover CK, Warrener P, VanDevanter DR, et al (2000). "A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis". Nature 405 (6789): 962–6. doi:10.1038/35016103. PMID 10879539.

See also

Tuberculosis treatment#Treatment of MDR-TB

This antiinfective drug article is a stub. You can help Wikipedia by expanding it.

Academic Dictionaries and Encyclopedias

PA 824

IUPAC name (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
Identifiers
CAS number	187235-37-6^Y
PubChem	456199
MeSH	PA+824
ChEMBL	CHEMBL227875^N
Jmol-3D images	Image 1
SMILES [O-][N+](=O)c1cn2C[C@@H](COc2n1)OCc3ccc(OC(F)(F)F)cc3
Properties
Molecular formula	C₁₄H₁₂F₃N₃O₅
Molar mass	359.258 g/mol
N 824 (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references