- CD61
Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), also known as ITGB3, is a human
gene . CD61 is acluster of differentiation found onthrombocyte s.PBB_Summary
section_title =
summary_text = The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [cite web | title = Entrez Gene: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3690| accessdate = ]ee also
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Glycoprotein IIb/IIIa References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Bray PF |title=Inherited diseases of platelet glycoproteins: considerations for rapid molecular characterization. |journal=Thromb. Haemost. |volume=72 |issue= 4 |pages= 492–502 |year= 1995 |pmid= 7878622 |doi=
*cite journal | author=Bennett JS |title=Platelet-fibrinogen interactions. |journal=Ann. N. Y. Acad. Sci. |volume=936 |issue= |pages= 340–54 |year= 2001 |pmid= 11460491 |doi=
*cite journal | author=Sajid M, Stouffer GA |title=The role of alpha(v)beta3 integrins in vascular healing. |journal=Thromb. Haemost. |volume=87 |issue= 2 |pages= 187–93 |year= 2002 |pmid= 11858476 |doi=
*cite journal | author=Quinn MJ, Byzova TV, Qin J, "et al." |title=Integrin alphaIIbbeta3 and its antagonism. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=23 |issue= 6 |pages= 945–52 |year= 2004 |pmid= 12637342 |doi= 10.1161/01.ATV.0000066686.46338.F1
*cite journal | author=Charakida M, Tousoulis D, Stefanadis C, Toutouzas P |title=The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease. |journal=Italian heart journal : official journal of the Italian Federation of Cardiology |volume=4 |issue= 1 |pages= 17–22 |year= 2003 |pmid= 12690916 |doi=
*cite journal | author=Smith FB, Connor JM, Lee AJ, "et al." |title=Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease. |journal=Thromb. Res. |volume=112 |issue= 4 |pages= 209–16 |year= 2004 |pmid= 14987913 |doi= 10.1016/j.thromres.2003.11.010
*cite journal | author=Fullard JF |title=The role of the platelet glycoprotein IIb/IIIa in thrombosis and haemostasis. |journal=Curr. Pharm. Des. |volume=10 |issue= 14 |pages= 1567–76 |year= 2004 |pmid= 15134555 |doi=
*cite journal | author=Cacciari B, Spalluto G |title=Non peptidic alphavbeta3 antagonists: recent developments. |journal=Curr. Med. Chem. |volume=12 |issue= 1 |pages= 51–70 |year= 2005 |pmid= 15638730 |doi=
*cite journal | author=Watson SP, Auger JM, McCarty OJ, Pearce AC |title=GPVI and integrin alphaIIb beta3 signaling in platelets. |journal=J. Thromb. Haemost. |volume=3 |issue= 8 |pages= 1752–62 |year= 2005 |pmid= 16102042 |doi= 10.1111/j.1538-7836.2005.01429.x
*cite journal | author=Bennett JS |title=Structure and function of the platelet integrin alphaIIbbeta3. |journal=J. Clin. Invest. |volume=115 |issue= 12 |pages= 3363–9 |year= 2006 |pmid= 16322781 |doi= 10.1172/JCI26989External links
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PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
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