Eight-cell stage

Eight-cell stage

The eight-cell stage is a period in embryonic development when the conceptus has undergone three cleavages from a single cell, resulting in eight cells. In some mammals, it is at this stage of development that the individual cells begin to adhere tightly, a process called compaction. [PMID 8793055; cite web|url=http://www.biolreprod.org/cgi/reprint/55/1/32.pdf|title=Compaction and Surface Polarity in the Human Embryo In Vitro|last=Handyside, A.H.|first=Nikas, G.|coauthors=Ao, A., Winston, R.M.L|date=1996|work=Biology of Reproduction|format=pdf] A single cell can be removed from a pre-compaction 8 cell embryo and used for genetic screening. [PMID 15569702]

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