Myomesin

Myomesin is an end line protein that is part of the M line. It is a protein found in the M-band of muscle sarcomeres in association with M-protein. It is found in both slow and fast muscle fibers while M-protein is only found in fast fibers.^[1] These proteins are thought to be involved in anchoring the thick filaments of the sarcomere (myosin) to other filaments, namely titin, stabilizing and aligning the structure.^[2] It may function as a molecular spring that protects the sarcomere and keeps it stable during intense or sustained stretching.^[3] While its specific function is still not completely understood, it has been shown that it is closely associated with myosin as it is present in all skeletal and cardiac muscle from the earliest stages of muscle tissue formation.

References

1. ^ Daniel Auerbach, Stefan Bantle, Stefan Keller, Vera Hinderling, Martin Leu, Elisabeth Ehler & Jean-Claude Perriard (1999). "Different domains of the M-band protein myomesin are involved in myosin binding and M-band targeting". Molecular Biology of the Cell 10 (5): 1297–1308. PMC 25262. PMID 10233145. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=25262. 
2. ^ "Muscle Proteins". Ohio State University. http://class.fst.ohio-state.edu/FST822/lecturesab/Muscl.htm. Retrieved December 9, 2010. 
3. ^ Roman Schoenauer, Patricia Bertoncini, Gia Machaidze, Ueli Aebi, Jean-Claude Perriard, Martin Hegner & Irina Agarkova (2005). "Myomesin is a molecular spring with adaptable elasticity" (PDF). Journal of Molecular Biology 349 (2): 367–379. doi:10.1016/j.jmb.2005.03.055. PMID 15890201. http://www.tcd.ie/Physics/People/Martin.Hegner/Schoenauer_JMB05.pdf. 

This protein-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Proteins Protein stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? MaxMara Art Prize for Women in association with the Whitechapel Bob Hicok Look at other dictionaries: myomesin — Protein (165kD) found in the M line of the sarcomere …   Dictionary of molecular biology MYOM1 — Myomesin 1 (skelemin) 185kDa, also known as MYOM1, is a human gene.cite web | title = Entrez Gene: MYOM1 myomesin 1 (skelemin) 185kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=8736| accessdate = ] PBB …   Wikipedia MYOM2 — Myomesin (M protein) 2, 165kDa, also known as MYOM2, is a human gene.cite web | title = Entrez Gene: MYOM2 myomesin (M protein) 2, 165kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=9172| accessdate = ] …   Wikipedia Sarcomere — A band redirects here. For other uses, see A band. Sarcomere Image of sarcomere Latin sarcomerum Code TH …   Wikipedia MYH9 — Myosin, heavy chain 9, non muscle Identifiers Symbols MYH9; DFNA17; EPSTS; FTNS; MGC104539; MHA; NMHC II A; NMMHCA External IDs …   Wikipedia AKAP13 — A kinase (PRKA) anchor protein 13, also known as AKAP13, is a human gene.cite web | title = Entrez Gene: AKAP13 A kinase (PRKA) anchor protein 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=11214|… …   Wikipedia M-line — Central part of the A band of striated muscle (and of the M band) : contains M line protein (myomesin, 165 kD), creatine kinase (40 kD), and glycogen phosphorylase b (90 kD). Involved in controlling the spacing between thick filaments …   Dictionary of molecular biology M-protein — (1) Galactoside carrier in E. coli. (2) Cell surface antigen of Brucella. (3) Structural protein in the M line of striated muscle (myomesin). (4) Cell wall protein of streptococci: antibody typing of the M protein is important in identification… …   Dictionary of molecular biology 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”