- Journal of Molecular Biology
Infobox Journal
discipline =Molecular biology
website = http://www.elsevier.com/locate/issn/0022-2836
link1 = http://www.sciencedirect.com/science/journal/00222836
link1-name = Content URL
publisher =Elsevier
country =
abbreviation = J. Mol. Biol.
history = 1959 to present
ISSN = The "Journal ofMolecular Biology " is ascientific journal published weekly byElsevier , under theAcademic Press imprint. It publishes original scientific research concerning studies of organisms or their components at the molecular level.Back issues are available online by subscription from 1993 onward. Previous issues are only available in print.
Some of the most highly cited articles that have appeared in the Journal of Molecular Biology since its inception in 1959 include:
*"On the nature of allosteric transitions: a plausible model," in 1965, in whichJacques Monod , Jeffries Wyman andJean-Pierre Changeux presented theMWC model , that explained the cooperativity exhibited by allosteric proteins, such ashemoglobin .
*"Detection of Specific Sequences Among DNA Fragments Separated by Gel-Electrophoresis," in 1975, in whichEdwin Southern presented the first description of nucleic acidblotting , a technique that revolutionized the field of molecular biology.
* "Identification of Common Molecular Subsequences," in 1981, in which theSmith-Waterman algorithm for determining the degree of homology of DNA, RNA, or protein sequences was first described.
* "Basic Local Alignment Search Tool," in 1990, in which the nucleic acid and protein homology search algorithm known asBLAST was originally described.External links
* [http://www.elsevier.com/locate/issn/0022-2836 Official website]
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