Sterol carrier protein

Sterol carrier protein

Pfam_box
Symbol = SCP2
Name =


width =200
caption = Sterol carrier protein 2
Pfam= PF02036
InterPro= IPR003033
SMART=
PROSITE = PDOC00092
SCOP = 1qnd
TCDB =
OPM family= 144
OPM protein= 2cx7
PDB=PDB3|1qndA:437-540 PDB3|1c44A:437-540 PDB3|1iktA:628-731PDB3|1pz4A:9-94 PDB3|2cx7A:9-105

Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes.

These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus.

This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipidscite journal |author=Johansson J, Wuthrich K, Szyperski T, Scheek S, Assmann G, Seedorf U |title=NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2 |journal=FEBS Lett. |volume=335 |issue=1 |pages=18–26 |year=1993 |pmid=8243660 |doi=10.1016/0014-5793(93)80431-S] .

Human proteins containing this domain

C20orf79; HSD17B4; HSDL2; SCP2; STOML1;

ee also

*Steroidogenic acute regulatory protein

References

External links

* [http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.e.bhf.b.A.html Sterol carrier proteins] in SCOP
* [http://www.sanger.ac.uk/cgi-bin/Pfam/getacc?PF02036 SCP-2 sterol transfer family] in Pfam
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