Dihydropteroate synthetase

Dihydropteroate synthetase

Dihydropteroate synthetase is an enzyme classified under EC number|2.5.1.15. It produces dihydropteroate in bacteria, but does not function in humans. This makes it a useful target for sulfonamide antibiotics, which compete with the PABA precursor.

It acts upon 4-Aminobenzoic acid (PABA} and dihydropteridine-hydroxymethyl-pyrophosphate.

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Dihydropteroate synthase — Tetrahydrofolate synthesis pathway Identifiers EC number …   Wikipedia

  • Dihydropteroate — IUPAC name 4 {[(2 amino 4 oxo 1,4,7,8 tetrahydropteridin 6 yl)methyl]amino}benzoic acid …   Wikipedia

  • Dihydropteroate synthase inhibitor — A dihydropteroate synthetase inhibitor is a drug that inhibits the action of dihydropteroate synthetase. Most are sulfonamides. Tetrahydrofolate synthesis pathway In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme …   Wikipedia

  • dihydropteroate — noun A pterin created from para aminobenzoic acid by the enzyme dihydropteroate synthetase, an important intermediate in folate synthesis …   Wiktionary

  • Dapsone — Systematic (IUPAC) name 4 [(4 aminobenzene)sulfonyl]aniline …   Wikipedia

  • Sulfonamide (medicine) — There are several sulfonamide based groups of drugs. The original antibacterial sulfonamides (sometimes called simply sulfa drugs) are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of… …   Wikipedia

  • Tetrahydrofolic acid — Chembox new ImageFile = Tetrahydrofolic acid.svg ImageSize = 250px IUPACName = OtherNames = Section1 = Chembox Identifiers CASNo = 29347 89 5 PubChem = 1129 SMILES = MeSHName = 5,6,7,8 tetrahydrofolic+acid Section2 = Chembox Properties Formula =… …   Wikipedia

  • List of antibiotics — Following is the list of antibiotics, sorted by class. The highest division is between bactericidal antibiotics and bacteriostatic antibiotics. Bactericidals kill bacteria directly where bacteriostatics prevent them from dividing. However, these… …   Wikipedia

  • Monoamine oxidase inhibitor — MAOI redirects here. For the Easter Island statues, see Moai. Monoamine oxidase Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. They are particularly effective in treating… …   Wikipedia

  • Phosphodiesterase inhibitor — A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”