Glycerol 3-phosphate

Glycerol 3-phosphate

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ImageFile = glycerol-3-phosphate.png ImageSize = 150px
IUPACName = 1,2,3-Propanetriol, 1- (dihydrogen phosphate)
OtherNames =
Glycerol-1-phosphate
Glycerophosphate
α-glycerolphosphate
Section1 = Chembox Identifiers
CASNo = 57-03-4
PubChem = 754
ChemSpiderID = 734
SMILES = OCC(O)COP(O)(O)=O
MeSHName = glycerol+3-phosphate

Section2 = Chembox Properties
Formula = C3H9O6P
MolarMass = 172.074
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Section3 = Chembox Hazards
Solubility =
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Glycerol 3-phosphate is a chemical intermediate in the glycolysis metabolic pathway. It should not be confused with the similarly named glycerate 3-phosphate or glyceraldehyde 3-phosphate.

Function

Glycerol 3-phosphate is produced from glycerol, the triose sugar backbone of triglycerides and glycerophospholipids, by the enzyme glycerol kinase. Glycerol 3-phospate may then be converted by dehydrogenation to dihydroxyacetone phosphate (DHAP) by the enzyme glycerol-3-phosphate dehydrogenase. DHAP can then be rearranged into glyceraldehyde 3-phosphate(GA3P) by triose phosphate isomerase(TIM), and feed into glycolysis.

The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in brain and skeletal muscle cells of mammals.

ee also

* Glycerol-3-phosphate dehydrogenase


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