Glycerol-3-phosphate cytidylyltransferase

In enzymology, a glycerol-3-phosphate cytidylyltransferase (EC number|2.7.7.39) is an enzyme that catalyzes the chemical reaction

:CTP + sn-glycerol 3-phosphate $ightleftharpoons$ diphosphate + CDP-glycerol

Thus, the two substrates of this enzyme are CTP and sn-glycerol 3-phosphate, whereas its two products are diphosphate and CDP-glycerol.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:sn-glycerol-3-phosphate cytidylyltransferase. Other names in common use include CDP-glycerol pyrophosphorylase, cytidine diphosphoglycerol pyrophosphorylase, cytidine diphosphate glycerol pyrophosphorylase, CTP:glycerol 3-phosphate cytidylyltransferase, and Gro-PCT. This enzyme participates in glycerophospholipid metabolism.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1COZ, PDB link|1N1D, and PDB link|2B7L.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|9027-11-6."

Gene Ontology (GO) codes