Protein K (porin)

Protein K (porin)

Protein K is a porin expressed in some pathogenic strains of E. coli bacteria. It has a molecular weight of about 40 kDa and is localized to the outer membrane, through which it allows both inorganic and organic ions to pass.

The strains in which protein K has been identified are "encapsulated", or surrounded by a poly-sialic acid capsule that renders them more resistant to phagocytosis by cells in the immune system.

References

* Whitfield C, Hancock RE, Costerson JW. (1983). Outer membrane protein K of Escherichia coli: purification and pore-forming properties in lipid bilayer membranes. "J Bacteriol" 156(2): 873-879
* Sutcliffe J, Blumenthal R, Walter A, Foulds J. (1983). Escherichia coli outer membrane protein K is a porin. "J Bacteriol" 156(2): 867-872
* Bliss JM, Solver RP. (1996). Coating the surface: a model for expression of capsular polysialic acid in Escherichia coli K1. "Mol Microbiol" 21:221.


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