Nucleoside-specific porin

Nucleoside-specific porin
Nucleoside-specific channel-forming protein, Tsx
1tly opm.gif
Identifiers
Symbol Channel_Tsx
Pfam PF03502
InterPro IPR003055
TCDB 1.B.10
OPM family 71
OPM protein 1tly

Nucleoside-specific porin (the tsx gene of Escherichia coli) is an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides[1]. The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. Tsx shows no significant similarities to general bacterial porins.

References

  1. ^ Bremer E, Martinussen J, Middendorf A, Valentin-Hansen P (1990). "Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli". Gene 96 (1): 59–65. doi:10.1016/0378-1119(90)90341-N. PMID 2265760. 

This article includes text from the public domain Pfam and InterPro IPR003055


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