10-Deacetylbaccatin

10-Deacetylbaccatin
IUPAC name (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)- 12b-(Acetyloxy)-12-(benzoyloxy)- 1,2a,3,4,4a,6,9,10,11,12,12a,12b- dodecahydro-4,6,9,11-tetrahydroxy- 4a,8,13,13-tetramethyl-7,11-methano- 5H-cyclodeca(3,4)benz(1,2-b) oxet-5-one
Other names 10-Deacetylbaccatin III 10-Deacetylbaccatine III
Identifiers
CAS number	32981-86-5 N
PubChem	154272
ChemSpider	135935 Y
ChEBI	CHEBI:18193 Y
ChEMBL	CHEMBL393912 Y
Jmol-3D images	Image 1
SMILES CC1=C2C(C(=O)C3 (C(CC4C(C3C(C(C2(C)C)(CC1O)O) OC(=O)C5=CC=CC=C5)(CO4) OC(=O)C)O)C)O
InChI InChI=1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1 Y Key: YWLXLRUDGLRYDR-ZHPRIASZSA-N Y
Properties
Molecular formula	C29H36O10
Molar mass	544.59
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. 10-Deacetylbaccatin III is used as a chemical intermediate in the preparation of the anti-cancer drug paclitaxel (Taxol).

External links

• PubChem 5316348 - 10-deacetylbaccatin VI

This article about a ketone is a stub. You can help Wikipedia by expanding it.v · Categories: Benzoates Alcohols Ketones Diterpenes Acetate esters Ketone stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Barry Dransfield Ford 4.4 Turbo Diesel Look at other dictionaries: 10-Deacetylbaccatin III — Strukturformel Allgemeines Name 10 Deacetylbaccatin III Summe …   Deutsch Wikipedia 10-deacetylbaccatin III 10-O-acetyltransferase — In enzymology, a 10 deacetylbaccatin III 10 O acetyltransferase (EC number|2.3.1.167) is an enzyme that catalyzes the chemical reaction:acetyl CoA + 10 deacetylbaccatin III ightleftharpoons CoA + baccatin IIIThus, the two substrates of this… …   Wikipedia Paclitaxel — Systematic (IUPAC) name (2α,4α,5β,7β,10β,13α) 4,10 bis(acetyloxy) …   Wikipedia Paclitaxel total synthesis — in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). [Note that the original publications about the total synthesis use the name taxol , which used to be the generic name before it was accepted as… …   Wikipedia 2alpha-hydroxytaxane 2-O-benzoyltransferase — In enzymology, a 2alpha hydroxytaxane 2 O benzoyltransferase (EC number|2.3.1.166) is an enzyme that catalyzes the chemical reaction:benzoyl CoA + 10 deacetyl 2 debenzoylbaccatin III ightleftharpoons CoA + 10 deacetylbaccatin IIIThus, the two… …   Wikipedia Natural product — Paclitaxel (Taxol) is a natural product derived from the Yew tree.[1] A natural product is a chemical compound or substance produced by a living organism found in nature that usually has a pharmacological or biological activity for use in… …   Wikipedia Nicolaou Taxol total synthesis — overview from raw material perspective. The Nicolaou Taxol total synthesis, published by K. C. Nicolaou and his group in 1994 concerns the total synthesis of Taxol. This organic synthesis was included in Nicolaou s book, Classics in Total… …   Wikipedia Taxus canadensis — Taxobox name = Taxus canadensis image width = 200px status = LR/lc | status system = IUCN2.3 regnum = Plantae divisio = Pinophyta classis = Pinopsida ordo = Pinales familia = Taxaceae genus = Taxus species = T. canadensis binomial = Taxus… …   Wikipedia List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia Paclitaxel — es un fármaco utilizado para el tratamiento del cáncer. Fue descubierto por el Research Triangle Institute (RTI) en 1968 cuando Monroe E. Wall y Mansukh C. Wani aislaron el compuesto que se encuentra en la corteza del Tejo del Pacífico, Taxus… …   Wikipedia Español 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”