- Christopher Chetsanga
-
Christopher J Chestanga Born 22 August 1935
Murehwa, ZimbabweResidence Zimbabwe Nationality Zimbabwean Fields Biochemistry, Molecular Biology Institutions University of Zimbabwe Alma mater University of California, Pepperdine University, University of Toronto Doctoral advisor - Doctoral students - Known for Discovery ot two enzymes involved in DNA repair, which earned him a nomination for the Nobel Prize in Physiology or Medicine [1] Notable awards UNESCO Gold Medal Award winner [2] Christopher J Chetsanga (born 1935 in Murehwa, Zimbabwe) is a preeminent Zimbabwean scientist.
Contents
Education
- 1965 obtained a BSc degree at the University of California and Pepperdine University in California, USA[3]
- 1965-1969 obtained MSc and PhD degrees in Biochemistry and Molecular Biology at the University of Toronto, Canada[3]
- 1969-1972 became a Post-doctoral Fellow, Department of Biochemistry and Molecular Biology at Harvard University[4]
Scientific Achievements
Discovered two enzymes involved in the repair of damaged DNA:
- Formamidopyrimidine DNA Glycosylase, which removes damaged 7-methylguanine from DNA (1979).[5]
- DNA cyclase, which recloses imidazole rings of guanine and adenine damaged by x-irradiation (1985).[6]
Work experience
- Assistant Professor, Associate Professor, Full Professor, University of Michigan, 1972–1983
- Professor of Biochemistry, University of Zimbabwe, 1983–1986
- Dean of Science University of Zimbabwe, (1986–1991)
- Pro Vice Chancellor, University of Zimbabwe, (1991–1993)[3]
- Director General, Scientific and Industrial Research and Development Center, Zimbabwe, 1993-2003[4]
References
- ^ "UGLIEST STEREOTYPE SHATTERED!". http://hrassoc.net/blog/modules/news/article.php?storyid=17. Retrieved 2009-09-22.
- ^ "ReNaissance Financial Holdings Limited". http://www.renaissance.co.zw/profiles/PROF.html. Retrieved 2009-09-22.
- ^ a b c "exco5_sc_candidate_shortcv.pdf" (PDF). Consultive Group on International Agricultural Research. p. 18. http://www.cgiar.org/exco/exco5/exco5_sc_candidate_shortcv.pdf. Retrieved 2008-06-02.
- ^ a b "::SIRDC". www.sirdc.ac.zw. http://www.sirdc.ac.zw/board/christopher.htm. Retrieved 2008-06-03.
- ^ Chetsanga, C.J.; Lindahl, T. (1979). "Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli". Nucleic Acids Res 6 (11): 3673–84. doi:10.1093/nar/6.11.3673. PMC 327965. PMID 386277. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=327965.
- ^ Chetsanga, C.J.; Grigorian, C. (1985). "In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation". Proceedings of the National Academy of Sciences of the United States of America 82 (3): 633–637. doi:10.1073/pnas.82.3.633. JSTOR 25324. PMC 397099. PMID 3856219. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=397099.
External links
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