Deoxyribonuclease II

deoxyribonuclease II alpha
Identifiers
Symbol	DNASE2
Alt. symbols	DNASE2A, DRN2, DNL, DNL2
Entrez	1777
HUGO	2960
OMIM	126350
RefSeq	NM_001375
UniProt	O00115
Other data
EC number	3.1.22.1
Locus	Chr. 19 p13.2

deoxyribonuclease II beta
Identifiers
Symbol	DNASE2B
Entrez	58511
HUGO	28875
OMIM	608057
RefSeq	NM_021233
UniProt	Q8WZ79
Other data
EC number	3.1.22.1
Locus	Chr. 1 p22.3

Deoxyribonuclease II, or Acid DNase, hydrolyzes deoxyribonucleotide linkages in native and denatured DNA, yielding products with 3'-phosphates. As the name implies, it is more effective at acid pH.

There are several known DNases II, including:

• DNase II alpha (usually just called DNase II)
• DNase II beta (also called DLAD, or DNase II-Like Acid DNase)

External links

• MeSH deoxyribonuclease+II

3.1.21-31: Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I · Deoxyribonuclease II · Deoxyribonuclease IV · Restriction enzyme · UvrABC endonuclease
Endoribonuclease	RNase III · RNase H (1, 2A, 2B, 2C) · RNase P · RNase A (1, 2, 3, 4/5) · RNase T1 · RNA-induced silencing complex
either deoxy- or ribo-	Aspergillus nuclease S1 · Micrococcal nuclease

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6