1-Aminocyclopropane-1-carboxylic acid

1-Aminocyclopropane-1-carboxylic acid

Chembox new
ImageFile = 1-Aminocyclopropane-1-carboxylic acid.png ImageSize = 130px
Name = 1-aminocyclopropane-1-carboxylic acid

Section1 = Chembox Identifiers
Abbreviations = ACC
CASNo = 22059-21-8
EINECS =
PubChem = 535
SMILES = C(O)(=O)C1(CC1)(N) cite journal | author = Caspi R, Foerster H, Fulcher CA, Hopkinson R, Ingraham J, Kaipa P, Krummenacker M, Paley S, Pick J, Rhee SY, Tissier C, Zhang P, Karp PD | title = MetaCyc: a multiorganism database of metabolic pathways and enzymes | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D511–6 | year = 2006 | pmid = 16381923 | doi = 10.1093/nar/gkj128 ]
Section2 = Chembox Properties
C = 4
H = 7
N = 1
O = 2
MolarMass = 101.1 Ref_N|2|c
MeltingPt =
Density =
IsoElectricPt =

1-Aminocyclopropane-1-carboxylic acid (ACC) is a disubstituted cyclic alpha-amino acid in which a three-membered cyclopropane ring is fuzed to the C(alpha)-atom of the amino acid.

ACC plays an important role in the biosynthesis of the plant hormone ethylene.cite journal | author = Yang S, Hoffman N | title = Ethylene biosynthesis and its regulation in higher plants | journal = Annu. Rev. Plant Physiol. | volume = 35 | issue = | pages = 155–189 | year = 1984| doi = 10.1146/annurev.pp.35.060184.001103 ] cite journal | author = Kende H | title = Ethylene biosynthesis | journal = Annu. Rev. Plant Physiol. | volume = 44 | issue = | pages = 283–307 | year = 1993| doi = 10.1146/annurev.pp.44.060193.001435 ] It is synthesized by the enzyme ACC synthase ( EC number|4.4.1.14) from methionine and converted to ethylene by ACC oxidase (EC number|1.14.17.4).cite journal | author = Kende H | title = Enzymes of Ethylene Biosynthesis | journal = Plant Physiol. | volume = 91 | issue = 1 | pages = 1–4 | year = 1989 | pmid = 16666977| doi = | issn = | url = http://www.plantphysiol.org/cgi/content/abstract/91/1/1 ]

ACC is also a non-physiological partial agonist of the mammalian NMDA receptor.cite journal | author = Inanobe A, Furukawa H, Gouaux E | title = Mechanism of partial agonist action at the NR1 subunit of NMDA receptors | journal = Neuron | volume = 47 | issue = 1 | pages = 71–84 | year = 2005 | pmid = 15996549 | doi = 10.1016/j.neuron.2005.05.022 ]


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