Pyrrolidine dithiocarbamate

Pyrrolidine dithiocarbamate
IUPAC name Pyrrolidine-1-carbodithioic acid
Other names Pyrrolidinedithiocarbamate; 1-Pyrrolidinecarbodithioic acid; Pyrrolidine dithiocarbamic acid
Identifiers
Abbreviations	PDTC
CAS number	25769-03-3
PubChem	65351
Jmol-3D images	Image 1
SMILES S=C(S)N1CCCC1
Properties
Molecular formula	C5H9NS2
Molar mass	147.26 g mol−1
Density	1.264 g/cm3
Boiling point	199.7 °C @ 760mmHg
Hazards
Flash point	74.6 °C
Y dithiocarbamate (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pyrrolidine dithiocarbamate (PDTC) is a chemical compound with the molecular formula C₅H₉NS₂. PDTC and its salts, such as ammonium pyrrolidinecarbodithioate, are used for a variety of biochemical applications including metal chelation, induction of G1 phase cell cycle arrest,^[1] and preventing induction of nitric oxide synthase.^[2]

References

1. ^ Moon, SK; Jung, SY; Choi, YH; Lee, YC; Patterson, C; Kim, CH (Feb 2004). "PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase". Journal of cellular physiology 198 (2): 310–23. doi:10.1002/jcp.10728. ISSN 0021-9541. PMID 14603533. 
2. ^ Ammonium pyrrolidinedithiocarbamate at Sigma-Aldrich