- Nemertelline
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Nemertelline 2-Pyridin-3-yl-3-(2-pyridin-3-ylpyridin-4-yl)pyridineSystematic name2-(Pyridin-3-yl)-4-[2-(pyridin-3-yl)pyridin-3-yl]pyridineIdentifiers CAS number 59697-14-2 PubChem 3042423 ChemSpider 2305572 KEGG C17016 MeSH Nemertelline Jmol-3D images Image 1 - C1=CN=CC(=C1)C1=CC(=CC=N1)C1=C(N=CC=C1)C1=CC=CN=C1
- InChI=1S/C20H14N4/c1-4-16(13-21-8-1)19-12-15(7-11-23-19)18-6-3-10-24-20(18)17-5-2-9-22-14-17/h1-14H
Key: SWWRILUGNLIYGG-UHFFFAOYSA-N
Properties Molecular formula C20H14N4 Molar mass 310.351 g/mol Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references Nemertelline is a neurotoxic tetra-pyridine compound originally found in the marine hoplonemertine worm Amphiporus angulatus.[1] These worms produce a variety of toxins which are used both in hunting their prey and in defending themselves from predators.[2] Interest in potential application of this compound as an antifouling agent for boats and other marine installations has led to attempts to produce it synthetically by convenient routes.[3]
References
- ^ Kem, WR; Scott, KN; Duncan, JH (1976). "Hoplonemertine worms -- a new source of pyridine neurotoxins". Experientia 32 (6): 684–6. doi:10.1007/BF01919831. PMID 181266.
- ^ Kem, WR; Soti, F; Rittschof, D (2003). "Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids". Biomolecular engineering 20 (4–6): 355–61. doi:10.1016/S1389-0344(03)00049-2. PMID 12919820.
- ^ Bouillon, A; Voisin, AS; Robic, A; Lancelot, JC; Collot, V; Rault, S (2003). "An efficient two-step total synthesis of the quaterpyridine nemertelline". The Journal of organic chemistry 68 (26): 10178–80. doi:10.1021/jo034805b. PMID 14682721.
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