Nemertelline

Nemertelline
Nemertelline
Identifiers
CAS number 59697-14-2
PubChem 3042423 YesY
ChemSpider 2305572 YesY
KEGG C17016
MeSH Nemertelline
Jmol-3D images Image 1
Properties
Molecular formula C20H14N4
Molar mass 310.351 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Nemertelline is a neurotoxic tetra-pyridine compound originally found in the marine hoplonemertine worm Amphiporus angulatus.[1] These worms produce a variety of toxins which are used both in hunting their prey and in defending themselves from predators.[2] Interest in potential application of this compound as an antifouling agent for boats and other marine installations has led to attempts to produce it synthetically by convenient routes.[3]

References

  1. ^ Kem, WR; Scott, KN; Duncan, JH (1976). "Hoplonemertine worms -- a new source of pyridine neurotoxins". Experientia 32 (6): 684–6. doi:10.1007/BF01919831. PMID 181266. 
  2. ^ Kem, WR; Soti, F; Rittschof, D (2003). "Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids". Biomolecular engineering 20 (4–6): 355–61. doi:10.1016/S1389-0344(03)00049-2. PMID 12919820. 
  3. ^ Bouillon, A; Voisin, AS; Robic, A; Lancelot, JC; Collot, V; Rault, S (2003). "An efficient two-step total synthesis of the quaterpyridine nemertelline". The Journal of organic chemistry 68 (26): 10178–80. doi:10.1021/jo034805b. PMID 14682721.