Natural sleep or anesthesia
- Natural sleep or anesthesia
-
Many similarities exist between natural sleep and anesthesia. During early parts of natural sleep, an individual is difficult to arouse. During general anesthesia, a patient cannot be aroused. Parts of the brain that are responsible for sleep are similar to areas that control general anesthesia. When one type of anesthesia, propofol, is used and there's natural sleep debt, it dissipates.[1] Though the propofol study showed sleep debt dissipation, the same was not found in a study using inhalation agents.[2] Specifically, A REM sleep deficit was apparent after exposure to isoflurane, sevoflurane or halothane and a NREM sleep deficit is seen after halothane.[3]
References
- ^ Tung A, Bergmann BM, Herrera S, Cao D, Mendelson WB (June 2004). "Recovery from sleep deprivation occurs during propofol anesthesia". Anesthesiology 100 (6): 1419–26. PMID 15166561.
- ^ Pick J, Chen Y, Moore JT, Sun Y, Wyner AJ, Friedman EB, Kelz MB (October 2011). "Rapid eye movement sleep debt accrues in mice exposed to volatile anesthetics". Anesthesiology 115 (4): 702–12. doi:10.1097/ALN.0b013e31822ddd72. PMID 21934405. Lay summary – journal's blog.
- ^ Brown EN, Lydic R, Schiff ND (December 2010). "General anesthesia, sleep, and coma". N. Engl. J. Med. 363 (27): 2638–50. doi:10.1056/NEJMra0808281. PMC 3162622. PMID 21190458. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3162622.
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