NADPH—cytochrome-c2 reductase

NADPH—cytochrome-c2 reductase
Identifiers
EC number	1.6.2.5
CAS number	37256-32-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a NADPH—cytochrome-c2 reductase (EC 1.6.2.5) is an enzyme that catalyzes the chemical reaction

NADPH + 2 ferricytochrome c₂ $\rightleftharpoons$ NADP⁺ + H⁺ + 2 ferrocytochrome c₂

Thus, the two substrates of this enzyme are NADPH and ferricytochrome c2, whereas its 3 products are NADP⁺, H⁺, and ferrocytochrome c2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a heme protein as acceptor. The systematic name of this enzyme class is NADPH:ferricytochrome-c2 oxidoreductase. Other names in common use include cytochrome c2 reductase (reduced nicotinamide adenine dinucleotide, phosphate), cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide, and phosphate, NADPH). It employs one cofactor, FAD.

References

• Sabo DJ, Orlando JA (1968). "Isolation, purification, and some properties of reduced nicotinamide adenine dinucleotide phosphate-cytochrome C2 reductase from Rhodopseudomonas spheroides". J. Biol. Chem. 243 (13): 3742–9. PMID 4385431.