Methylarginine

Methylarginine
IUPAC name (2S)-2-Amino-5-[(N′-methylcarbamimidoyl)amino]pentanoic acid
Other names Targinina; Targininum; Targinine; omega-N-Methylarginine; L-Monomethylarginine; N-Methyl-L-arginine; N-Monomethyl-L-arginine; NG-monomethyl-L-arginine
Identifiers
Abbreviations	L-NMMA
CAS number	17035-90-4 Y
PubChem	132862
ChEMBL	CHEMBL256147 N
Jmol-3D images	Image 1
SMILES CN=C(N)NCCC[C@@H](C(=O)O)N
Properties
Molecular formula	C7H16N4O2
Molar mass	188.23 g/mol
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

N-Methylarginine is an inhibitor of nitric oxide synthase.^[1] Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide.

See also

• Asymmetric dimethylarginine

References

1. ^ Toutouzas, K.; Riga, M.; Stefanadi, E.; Stefanadis, C. (2008). "Asymmetric dimethylarginine (ADMA) and other endogenous nitric oxide synthase (NOS) inhibitors as an important cause of vascular insulin resistance". Hormone and Metabolic Research 40 (9): 655–659. doi:10.1055/s-0028-1083814. PMID 18792879.