Dundee Cell Products

Dundee Cell Products
Dundee Cell Products Ltd
DCP Logo (200x104).jpg
Type Private Company
Founded 2006
Location Dundee, Scotland, UK
Industry Biotechnology
Products Biochemical reagents, procedure kits, specialized research products
Services Proteomics, DNA cloning, gene synthesis, antibody development, protein expression and purification
Website http://www.dundeecellproducts.com/

Dundee Cell Products[1] (DCP) is a biotechnology company headquartered in Dundee, Scotland, United Kingdom. The company is a bioreagents and life sciences services company which commercialises research tools for biochemistry, molecular biology and cell biology research, and provides services in these areas to the life sciences community. The company’s key business activities include research and development of new innovative products and services, commercialization of products in-licensed from academic institutions, distribution of life sciences research products from commercial partners and supply of contract research services to both academic and pharmaceutical/biotechnology companies customers.

Contents

History

Dundee Cell Products Ltd was founded in 2006 as a spinout of the internationally renowned College of Life Sciences[2] of the University of Dundee by Dr Paul Ajuh and Prof. Angus Lamond, scientists working at the institution. Since spinout the company has maintained close interactions with researchers at the institution and a strong relationship with the University. In 2007 the company secured equity investment funding from a syndicate of angel investors to finance and expand its activities with follow up investment secured in 2009 from angel investors and the Scottish Co-investment Fund (SCF).[3] The investment was secured to support the business’s growth plans. Over the last four years DCP has enjoyed significant growth in its products portfolio and turnover.

Research and Innovation

In the last 2–3 years, the company has developed and commercialized several new products e.g. SILAC ready to use media and has been involved in proteomics research collaborations with scientists in both academic institutions and pharmaceutical companies. Some of these projects have been designed to investigate the effects of virus infections on cellular proteomes in order to elucidate the mechanisms and cellular pathways involved in virus–host factor interactions.[4] DCP has also collaborated in a phosphoproteomics project[5] designed to study the molecular mechanisms in the pathogenesis of transmissible spongiform encephalopathies (TSEs) or prion disease. Transmissible spongiform encephalopathies are fatal diseases associated with the conversion of the cellular prion protein to an abnormal prion protein leading to damage of brain and neural tissue. Examples of prion diseases include bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans. There is currently no treatment for prion diseases, which are usually fatal to the host.

Current R&D projects within the company have been focused on developing applications for SILAC quantitative proteomics in predictive toxicology. These projects are designed to provide data that will be used in developing predictive models for drug toxicity early on during the drug discovery and development process.

Portfolio

DCP initially developed antibodies, mammalian cell fractions for precursor mRNA splicing research and tissue culture media specifically formulated for SILAC quantitative proteomics. The first products commercialized by the company came from the research interests of the founding scientists who saw an opportunity in the market for developing and commercializing high quality research products and services in the research area to other colleagues. The company has subsequently expanded its products and services portfolio into many other areas of life sciences research to better cover the needs of its customers.

Product lines

Dundee Cell Products commercializes a broad range of life sciences research products (many of which have been developed in-house) including cell culture media for quantitative proteomics, mammalian cell fractions e.g. nuclei, nucleoli, mitochondria and cell fractions for quantitative proteomics, antibodies, recombinant proteins and molecular biology kits for DNA and RNA purification. The company’s SILAC ready to use media have been specially formulated to facilitate the use of SILAC technology by non-specialists in proteomics and scientists who are interested in the application of unbiased high throughput quantitative proteomics approaches in their R&D activities.

Research services

As well as offering research products, the company’s portfolio has grown to include research services designed to accelerate the research activities of scientists in both the academic and biotech/pharmaceutical industry sectors. Some of the research services that DCP offers include gene synthesis, DNA cloning, recombinant protein expression and purification, stable cell line development, custom monoclonal and polyclonal antibody development and various proteomics services[6] i.e. both quantitative (e.g. SILAQTM, iTRAQ, ICAT, label-free) and qualitative. In collaboration with scientists at the University of Dundee, the company is developing novel and innovative products and services in the areas of proteomics, molecular biology and cell biology focused on the needs of research scientists in academic institutions as well as those in biotechnology and pharmaceutical companies.

Corporate Information

Brenda Reynolds - Chairman
Paul Ajuh - CEO
Angus Lamond - CSO
Robert Preston - Non Executive Director
Stewart Brymer - Non Executive Director

References

  1. ^ http://www.dundeecellproducts.com/
  2. ^ http://www.lifesci.dundee.ac.uk/
  3. ^ http://www.scottish-enterprise.com/fund-your-business/scottish-investment-bank/scif.aspx
  4. ^ Emmott E., Rodgers M.A., Macdonald A., McCrory S., Ajuh P., Hiscox J.A. (2010) Mol. Cell. Proteomics, 9, 1920-1936
  5. ^ Wagner W., Ajuh P., Löwer J., Wessler S. (2010) Cell. Commun. Signal. 8, 28
  6. ^ http://www.dundeecellproteomics.com/

Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • University of Dundee — Latin: Universitas Dundensis Motto Latin: Magnificat anima mea dominum[1] Motto in English …   Wikipedia

  • Life Sciences — ▪ 2009 Introduction Zoology       In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …   Universalium

  • Cyclacel — Pharmaceuticals, Inc. Type Public (NASDAQ: CYCC) Industry Biotechnology Founded …   Wikipedia

  • Stars and planetary systems in fiction — The planetary systems of stars other than the Sun and the Solar System are a staple element in much science fiction. Contents 1 Overview 1.1 The brightest stars …   Wikipedia

  • Lipid — Structures of some common lipids. At the top are oleic acid[1] and cholesterol.[2] The middle structure is a triglyceride composed of oleoyl, stearoyl, and palmitoyl chains at …   Wikipedia

  • Late-May 2008 tornado outbreak sequence — A tornado in Kansas on May 22, 2008 Date of tornado outbreak: May 22–31, 2008 Duration1: 9 days Maximum rated t …   Wikipedia

  • performing arts — arts or skills that require public performance, as acting, singing, or dancing. [1945 50] * * * ▪ 2009 Introduction Music Classical.       The last vestiges of the Cold War seemed to thaw for a moment on Feb. 26, 2008, when the unfamiliar strains …   Universalium

  • Mars, Incorporated — Mars, Inc. Type Private Industry Confectionery manufacturing Founded …   Wikipedia

  • Sheridan Snyder — Infobox Person name = Sheridan Snyder birth date = birth date and age|1936|10|20|df=yes birth place = Long Island, New York occupation = Chairman and CEO, BioCatalyst InternationalDr. Sheridan Gray Sherry Snyder OBE, LLB (born October 20th, 1936) …   Wikipedia

  • Australia — /aw strayl yeuh/, n. 1. a continent SE of Asia, between the Indian and the Pacific oceans. 18,438,824; 2,948,366 sq. mi. (7,636,270 sq. km). 2. Commonwealth of, a member of the Commonwealth of Nations, consisting of the federated states and… …   Universalium

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”