- Disorders of consciousness
Disorders of consciousness are medical conditions that inhibit consciousness. This category generally includes minimally conscious state and persistent vegetative state, but sometimes also includes the less severe locked-in syndrome and more severe chronic coma. Differential diagnosis of these disorders is an active area of biomedical research. Finally, brain death results in an irreversible disruption of consciousness. While other conditions may cause a moderate deterioration (e.g., dementia and delirium) or transient interruption (e.g., grand mal and petit mal seizures) of consciousness, they are not included in this category.
Minimally conscious state
In a minimally conscious state, the patient has intermittent periods of awareness and wakefulness and displays some meaningful behavior.
Persistent vegetative state
In a persistent vegetative state, the patient has sleep-wake cycles, but lacks awareness and only displays reflexive and non-purposeful behavior.
In chronic coma the patient lacks awareness and sleep-wake cycles and only displays reflexive behavior.
After brain death the patient lacks awareness, sleep-wake cycles, and behavior.
Society and culture
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- ^ Monti MM, Vanhaudenhuyse A, Coleman MR, Boly M, Pickard JD, Tshibanda L, Owen AM, Laureys S (18 Feb 2010). "Willful modulation of brain activity in disorders of consciousness". N Engl J Med 362 (7): 579–589. doi:10.1056/NEJMoa0905370. PMID 20130250.
- ^ Seel RT, Sherer M, Whyte J, Katz DI, Giacino JT, Rosenbaum AM, Hammond FM, Kalmar K, Pape TL, et al. (Dec 2010). "Assessment scales for disorders of consciousness: evidence-based recommendations for clinical practice and research". Arch Phys Med Rehabil 91 (12): 1795–1813. doi:10.1016/j.apmr.2011.01.002. PMID 21112421.
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