Dipeptidyl-peptidase IV family

Dipeptidyl peptidase IV (DPP IV) N-terminal region
porcine dipeptidyl peptidase iv (cd26) in complex with 4-(2-aminoethyl)-benzene sulphonyl fluoride (aebsf)
Identifiers
Symbol	DPPIV_N
Pfam	PF00930
Pfam clan	CL0186
InterPro	IPR002469
PROSITE	PDOC00587
MEROPS	S9
SCOP	1n1m
Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary

In molecular biology, the dipeptidyl-peptidase IV family is a family of serine peptidases which belong to MEROPS peptidase family S9 (clan SC), subfamily S9B (dipeptidyl-peptidase IV). The protein fold of the peptidase domain for members of this family resembles that of serine carboxypeptidase D, the type example of clan SC. The type example of this family is Dipeptidyl peptidase-4.^[1]

Human proteins in this family are:

• Dipeptidyl peptidase-4
• Dipeptidyl peptidase 8
• Dipeptidyl peptidase 9
• Inactive dipeptidyl peptidase 10
• Dipeptidyl aminopeptidase-like protein 6
• Seprase

External links

• MEROPS entry for family S9B

References

1. ^ Misumi, Y.; Hayashi, Y.; Arakawa, F.; Ikehara, Y. (1992). "Molecular cloning and sequence analysis of human dipeptidyl peptidase IV, a serine proteinase on the cell surface". Biochimica et biophysica acta 1131 (3): 333–336. PMID 1352704.  edit

This article includes text from the public domain Pfam and InterPro IPR002469