DPP6

DPP6
Dipeptidyl-peptidase 6

PDB rendering based on 1xfd.
Identifiers
Symbols DPP6; DPPX; FLJ55680; MGC46605; VF2
External IDs OMIM126141 MGI94921 HomoloGene22560 GeneCards: DPP6 Gene
RNA expression pattern
PBB GE DPP6 207789 s at tn.png
PBB GE DPP6 gnf1h05777 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1804 13483
Ensembl ENSG00000130226 ENSMUSG00000061576
UniProt P42658 Q5U4C2
RefSeq (mRNA) NM_001039350.1 NM_010075
RefSeq (protein) NP_001034439.1 NP_034205
Location (UCSC) Chr 7:
153.58 – 154.69 Mb
Chr 5:
27.14 – 28.05 Mb
PubMed search [1] [2]

Dipeptidyl aminopeptidase-like protein 6 is a protein that in humans is encoded by the DPP6 gene.[1][2]

This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[2]

References

Further reading




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Look at other dictionaries:

  • Dipeptidyl peptidase — is a type of enzyme classified under EC 3.4.14. Types include: Cathepsin C, dipeptidyl peptidase 1[1] DPP3, dipeptidyl peptidase 3 Dipeptidyl peptidase 4 DPP6, dipeptidyl peptidase 6 DPP7, dipeptidyl peptidase 7 DPP8, dipeptidyl peptidase 8 DPP9 …   Wikipedia

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