Dictyostelium class II RNA

Class II RNA
Class II RNA conserved secondary structure
Identifiers
Symbol	?
Other data
RNA type	Cis-reg
Domain(s)	Dictyostelium discoideum

The class II RNA is a non-coding RNA. This family was identified using shotgun sequencing of full-length cDNA libraries of small RNAs (sRNA) from the social amoeba Dictyostelium discoideum.^[1] The RNAs are 59-60 nucleotides in length. A Northern blot analysis showed that this ncRNA was expressed in all stages of development and that, like Dictyostelium class I RNA, class II is strongly localised in the cytoplasm.^[1] Dictyostelium class I and II share a consensus sequence (5'-CCUUACAGCAA-3') which is found in an 'open' area of the secondary structure of both molecules. The function of this RNA is unknown.^[1]

See also

• Dictyostelium class I RNA
• non-coding RNA

References

1. ^ ^{a b c} Aspegren A, Hinas A, Larsson P, Larsson A, Söderbom F (2004). "Novel non-coding RNAs in Dictyostelium discoideum and their expression during development". Nucleic Acids Res. 32 (15): 4646–56. doi:10.1093/nar/gkh804. PMC 516072. PMID 15333696. http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=15333696. Retrieved 2010-07-22. 

Further reading

• Larsson P, Hinas A, Ardell DH, Kirsebom LA, Virtanen A, Söderbom F (June 2008). "De novo search for non-coding RNA genes in the AT-rich genome of Dictyostelium discoideum: performance of Markov-dependent genome feature scoring". Genome Res. 18 (6): 888–99. doi:10.1101/gr.069104.107. PMC 2413156. PMID 18347326. http://www.genome.org/cgi/pmidlookup?view=long&pmid=18347326. Retrieved 2010-07-22. 
• Hinas A, Söderbom F (March 2007). "Treasure hunt in an amoeba: non-coding RNAs in Dictyostelium discoideum". Curr. Genet. 51 (3): 141–59. doi:10.1007/s00294-006-0112-z. PMID 17171561. 
• Mosig A, Sameith K, Stadler P (February 2006). "Fragrep: an efficient search tool for fragmented patterns in genomic sequences". Genomics Proteomics Bioinformatics 4 (1): 56–60. doi:10.1016/S1672-0229(06)60017-X. PMID 16689703. http://linkinghub.elsevier.com/retrieve/pii/S1672-0229(06)60017-X. Retrieved 2010-07-22. 

External links

• Sequence Ontology page for Class II RNA
• Rfam page for D. discoideum sRNA DdR35