Danny Welch

Danny Welch

Danny Ray Welch,[1] PhD is an American Cancer Biologist and is the Leonard H. Robinson Endowed Chair and Professor of Pathology, Cell Biology, and Pharmacology & Toxicology at the University of Alabama at Birmingham.[2] Welch is also a Senior Scientist at the Comprehensive Cancer Center, Center for Metabolic Bone Disease, Skin Diseases Research Center, Gene Therapy Center, Cell Adhesion and Matrix Research Center, Biomatrix Engineering and Regenerative Medicine Center, and Center for Biophysical Sciences and Engineering at UAB [1]. His research is in the area of Metastasis Suppressor Genes and the biology of metastasis.

He is best known for his discovery of 4 of the 24 known metastasis suppressor genes. By definition, these genes suppress metastasis without suppressing growth of the primary tumor. He is also well known for his work in defining the characters of cancer metastasis, and for his mentoring.

He is the author of the book "Cancer Metastasis -- Related Genes" (CANCER METASTASIS—BIOLOGY AND TREATMENT Volume 3) by Kluwer Academic Publications (Now Springer). He has authored over 140 original research papers in the area of cancer biology and metastasis. Welch is one of the few researchers whose research has focused on unraveling the biology of cancer metastasis from the very beginning of his research career.

Selected published works

  • Bodenstine TM, Welch DR. Metastasis suppressors and the tumor microenvironment. Cancer Microenviron. 2008 Dec;1(1):1-11.
  • Shin R, Welch DR, Mishra VK, Nash KT, Hurst DR, Rama Krishna N. Clin Exp Metastasis. 2009 Mar 24
  • Stafford LJ, Vaidya KS, Welch DR. Metastasis suppressors genes in cancer.Int J Biochem Cell Biol. 2008;40(5):874-91
  • Vaidya KS, Welch DR. Metastasis suppressors and their roles in breast carcinoma. J Mammary Gland Biol Neoplasia. 2007 Sep;12(2-3):175-90.
  • Eccles SA, Welch DR. Metastasis: recent discoveries and novel treatment strategies. Lancet. 2007 May 19;369(9574):1742-57
  • Rinker-Schaeffer CW, O'Keefe JP, Welch DR, Theodorescu D. Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application. Clin Cancer Res. 2006 Jul 1;12(13):3882-9.

References


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