Human umbilical vein graft
- Human umbilical vein graft
A human umbilical vein graft (HUVG) is a specially prepared human umbilical vein that is used as a vascular graft. HUVGs have found use in arteriovenous fistulae[Rubio PA, Farrell EM. Modified human umbilical vein graft arteriovenous fistulae as a source of angioaccess in maintenance hemodialysis. Cardiovasc Dis. 1980 Mar;7(1):51-57. PMID 15216281. [http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=15216281 Full Text] .] (for patients with ESRD undergoing hemodialysis), as an interposition graft between the subclavian artery and pulmonary artery (in the Blalock-Taussig shunt procedure][Leao LE, Andrade JC, Succi JE, Cueva CC, Ribeiro EE, Carvalho AC, Buffolo E. Modified Blalock-Taussig shunt with an umbilical vein graft. Tex Heart Inst J. 1985 Mar;12(1):65-71. PMID 15227043. [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=341796 Full Text] .] ), and for peripheral bypass graft surgery, when the great saphenous vein (the preferred conduit) is unavailable or unusable.]HUVGs for peripheral bypass grafts are second only to the saphenous vein for long-term patency. [Neufang A, Espinola-Klein C, Dorweiler B, Reinstadler J, Pitton M, Savvidis S, Fischer R, Vahl C, Schmiedt W. Sequential femorodistal composite bypass with second generation glutaraldehyde stabilized human umbilical vein (HUV). Eur J Vasc Endovasc Surg. 2005 Aug;30(2):176-83. PMID 15950502.] However, they do have some tendency to form aneurysms and require more delicate handling than synthetic graft material from PETE (Dacron) or PTFE.
References
External links
* [http://www.braile.com.br/INGLES/veiaumbili.htm Umbilical vein graft] - a picture, specifications and uses. Braile Biomedica.
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