- dTDP-4-amino-4,6-dideoxygalactose transaminase
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dTDP-4-amino-4,6-dideoxygalactose transaminase Identifiers EC number 2.6.1.59 CAS number 72560-97-5 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a dTDP-4-amino-4,6-dideoxygalactose transaminase (EC 2.6.1.59) is an enzyme that catalyzes the chemical reaction
- dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate
dTDP-4-dehydro-6-deoxy-D-galactose + L-glutamate
Thus, the two substrates of this enzyme are dTDP-4-amino-4,6-dideoxy-D-galactose and 2-oxoglutarate, whereas its two products are dTDP-4-dehydro-6-deoxy-D-galactose and L-glutamate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase. Other names in common use include thymidine diphosphoaminodideoxygalactose aminotransferase, and thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase. It employs one cofactor, pyridoxal phosphate.
References
- Oashi H, Matsuhashi M, Matsuhashi S (1971). "Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis". J. Biol. Chem. 246 (8): 2325–30. PMID 4928644.
This transferase article is a stub. You can help Wikipedia by expanding it. - dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate
