Coverage probability

In statistics, the coverage probability of a confidence interval is the proportion of the time that the interval contains the true value of interest.^[1] For example, suppose our interest is in the mean number of months that people with a particular type of cancer remain in remission following successful treatment with chemotherapy. The confidence interval aims to contain the unknown mean remission duration with a given probability. This is the "confidence level" or "confidence coefficient" of the constructed interval which is effectively the "nominal coverage probability" of the procedure for constructing confidence intervals. The "nominal coverage probability" is often set at 0.95. The coverage probability is the actual probability that the interval contains the true mean remission duration in this example.

If all assumptions used in deriving a confidence interval are met, the nominal coverage probability will equal the coverage probability (termed "true" or "actual" coverage probability for emphasis). If any assumptions are not met, the actual coverage probability could either be less than or greater than the nominal coverage probability. When the actual coverage probability is greater than the nominal coverage probability, the interval is termed "conservative", if it is less than the nominal coverage probability, the interval is termed "anti-conservative", or "permissive."

A discrepancy between the coverage probability and the nominal coverage probability frequently occurs when approximating a discrete distribution with a continuous one. The construction of binomial confidence intervals is a classic example where coverage probabilities rarely equal nominal levels.^[2][3][4] For the binomial case, several techniques for constructing intervals have been created. The Wilson or Score confidence interval is one well known construction based on the normal distribution. Other constructions include the Wald, exact, Agresti-Coull, and likelihood intervals. While the Wilson interval may not be the most conservative estimate, it produces average coverage probabilities that are equal to nominal levels while still producing a comparatively narrow confidence interval.

The "probability" in coverage probability is interpreted with respect to a set of hypothetical repetitions of the entire data collection and analysis procedure. In these hypothetical repetitions, independent data sets following the same probability distribution as the actual data are considered, and a confidence interval is computed from each of these data sets.

See also

• Binomial proportion confidence interval

References

1. ^ Dodge, Y. (2003) The Oxford Dictionary of Statistical Terms, OUP. ISBN 0-19-920613-9
2. ^ Agresti, Alan; Coull, Brent (1998). "Approximate Is Better than "Exact" for Interval Estimation of Binomial Proportions". The American Statistician 52 (2): 119–126. doi:10.2307/2685469. JSTOR 2685469. 
3. ^ Brown, Lawrence; Cai, T. Tony; DasGupta, Anirban (2001). "Interval Estimation for a binomial proportion". Statistical Science 16 (2): 101–117. doi:10.1214/ss/1009213286. http://www-stat.wharton.upenn.edu/~tcai/paper/Binomial-StatSci.pdf. 
4. ^ Newcombe, Robert (1998). "Two-sided confidence intervals for the single proportion: Comparison of seven methods.". Statistics in Medicine 17 (8): 857–872. doi:10.1002/(SICI)1097-0258(19980430)17:8<857::AID-SIM777>3.0.CO;2-E. PMID 9595616. http://www3.interscience.wiley.com/journal/3156/abstract.